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Wachtel RE, Dexter F: Numerous studies have considered opportunity costs of operating time. Surgery Kasuya J, Kaas GA, Kitamoto T: A putative amino acid transporter of the solute carrier 6 family is upregulated by lithium and is required for resistance to lithium toxicity in Drosophila. Neuroscience 2009 Oct 20; 163(3):825-37 Dexter F, Epstein RH, Elgart RL, Ledolter J: Forecasting and perception of average and latest hours worked by on-call anesthesiologists. Anesth Analg 2009 Oct; 109(4):1246-52 Campos JH: An update on robotic thoracic surgery and anesthesia. Curr Opin Anaesthesiol 2009 Oct 19; (): Neuronal mechanisms of learning and memory revealed by spatial and temporal suppression of neurotransmission using shibire, a temperature-sensitive dynamin mutant gene in Drosophila melanogaster.
Kasuya J, Ishimoto H, Kitamoto T.
Front Mol Neurosci. 2009;2:11. Epub 2009 Aug 20.
PMID: 19738923 [PubMed - in process]
The Drosophila TRPA channel, Painless, regulates sexual receptivity in virgin females.
Sakai T, Kasuya J, Kitamoto T, Aigaki T.
Genes Brain Behav. 2009 Jul;8(5):546-57. Epub 2009 May 8.
PMID: 19531155 [PubMed - in process]
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The Department of Anesthesia at the University of Iowa is a leader in clinical and basic science research. Clinical investigations occur in all subspecialties including critical care and cardiothoracic, neurosurgical, and regional anesthesia. Basic science research topics are pain, analgesic pharmacology and learning and memory. There is an emphasis on training physicians and scientists on the fundamentals of basic and clinical research. The Department of Anesthesia is keenly interested in providing residents and fellows with the background for developing a career in research.
Surgical Intensive Care Unit Research
Operations Research
Pain Research
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| Grants Recently Awarded and Submitted |
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Grants Recently Awarded (Clinical)
| 09/2009: |
American Burn Association Grant, $25,000, Anthony Han, PI, “Clinical Pharmacology of Ketamine for Procedural Sedation in the Pediatric Burn Patients.” |
| 2008: |
CCOM Grant, $10,000, Robert From, PI, “A comparison of teaching methods in Anesthesia.” |
Grants Recently Awarded (Basic)
| 12/2009: |
NIH, $1,687,500, Donna Hammond, PI, “Opioid Mechanisms of Analgesia.” |
| 07/2009: |
NIH, $1,095,000, Toshihiro Kitamoto, PI, “Studies of Genes Involved in the Lithium Responsive Neurological Process.” |
| 07/2009: |
NIH T32, Donna Hammond, PI, “Interdisciplinary Training Program in Pain Research,” 4 trainee positions supported. |
| 05/2009: |
2009 IASP Research grant funded by the ScanDesign by Inger and Jens Bruun Foundation, $10,000, Timothy Brennan, PI. “Translational Mechanisms for Postoperative Pain.” |
| 03/2009: |
Kai Pharmaceuticals, $38,048, Timothy Brennan, PI, “Mechanism for Postoperative Pain.” |
| 02/2009: |
Carver Medical Research Initiative Grant, $30,000, 2 years, Toshihiro Kitamoto, PI, “Function and Regulation of the Lithium-inducible SLC6 Transporter.” |
| 02/2009: |
Carver Medical Research Initiative Grant, $24,000, 2 years, Max Baker, PI, “Novel Anticonvulsant Hydroxyl Trifluorethyl Phenolic Compounds.” |
Submitted Grants
| 07/06/2009: |
March of Dimes, Joss Thomas, PI, “Iowa Outcomes with Anesthesia (IOWA) study.” |
| 06/01/2009: |
Anesthesia Patient Safety Foundation, Mazen Maktabi, PI, “An Epidemiological Study of Preoperative Cognitive Impairment as a Risk Factor for Postoperative Delirium Older Adults Undergoing Noncardiac Surgery.” |
| 06/01/2009: |
NIH ARRA Grant, James Bates, Co-I, Project 3 of PPG: “Cellular S-nitrosothiol Signaling in Respiratory Biology.” |
| 05/29/2009: |
NIH ARRA Grant, Douglas Merrill, PI, “Validation of Driving Simulation as an Evaluation of Cognitive Recovery Following Sedation in Elderly Patients.” |
| 04/30/2009: |
NIH Challenge Grant, Anthony Han, PI, “Optimal LMWH in Patients with Major Burns: A New Dosing Guideline for Enoxaparin.” |
| 04/30/2009: |
NIH Challenge Grant, Chiedozie Udeh, PI, “Adjunctive Hyperbaric Oxygen in the Management of Infected Pancreatic Pseudocysts.” |
| 04/30/2009: |
NIH Challenge Grant, Timothy Brennan, PI, Max Baker, Co-I, “Validation of a Rat Model for Perioperative Pain after Lumbar Laminectomy.” |
| 03/03/2009: |
NIH R01, Timothy Brennan, PI, “Nociception from Deep Muscle Incision.” |
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| Investigator Spotlight: Max T. Baker, Ph.D. |
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 I received my doctorate in pharmacology at the University of Georgia College of Pharmacy studying the effects of dietary fats on carcinogen metabolic activation. After a postdoctoral fellowship at the Mayo Clinic, where I studied the metabolism of anesthetics and halogenated compounds by the cytochrome P450 enzyme system, I came to The University of Iowa in 1984. At the time, there was interest in the metabolism and toxicity of small fluorinated compounds as they were employed not only as anesthetics but as the new non-chlorinated refrigerant substitutes. Read more...
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