Login   
You are here: People » Faculty
Search  for  


Mohamed M. Ghoneim, M.D.
Professor Emeritus


Contact Information
Office Address: 6411 JCP
Phone Number: (319) 356-2197

Email Me

Education
Medical School
  • Ain Shams University
Residencies
  • Ain Shams University Hospitals, Cairo, Egypt
  • Nuffield Department of Anaesthesia, Oxford, U.K.
Research Interests
  • Effects of drugs on learning, memory and cognition
  • Effects of anesthesia and surgery on mental functions
Appointments
  • The University of Iowa College of Medicine 1967-present
Publications
  1. Ghoneim MM, Block RI, Haffarnan M, Mathews MJ: Awareness during anesthesia: risk factors, causes and sequelae: a review of reported cases in the literature. Anesth Analg 2009 Jan 20


  2. Ghoneim MM: Incidence of and risk factors for awareness during anaesthesia. Best Pract Res Clin Anaesthesiol 2007 Sep 29


  3. Ghoneim MM, Block RI: Immediate peri-operative memory. Acta Anaesthesiol Scand 2007 Aug 19


  4. Ghoneim MM: Drugs and human memory (part 2). Clinical, theoretical, and methodologic issues. Anesthesiology 2004 Apr 29


  5. Ghoneim MM: Drugs and human memory (part 1): Clinical, theoretical, and methodologic issues. Anesthesiology 2004 Apr 17


  6. Block RI, Erwin WJ, Ghoneim MM: Chronic drug use and cognitive impairments. Pharmacol Biochem Behav 2002 Aug 2


  7. Block RI, O'Leary DS, Hichwa RD, Augustinack JC, Boles Ponto LL, Ghoneim MM, Arndt S, Hurtig RR, Watkins GL, Hall JA, Nathan PE, Andreasen NC: Effects of frequent marijuana use on memory-related regional cerebral blood flow. Pharmacol Biochem Behav 2002 Mar 20


  8. Block RI, O'Leary DS, Hichwa RD, Augustinack JC, Ponto LL, Ghoneim MM, Arndt S, Ehrhardt JC, Hurtig RR, Watkins GL, Hall JA, Nathan PE, Andreasen NC: Cerebellar hypoactivity in frequent marijuana users. Neuroreport 2000 Mar 20


  9. Ghoneim MM, Block RI, Dhanaraj VJ, Todd MM, Choi WW, Brown CK: Auditory evoked responses and learning and awareness during general anesthesia. Acta Anaesthesiol Scand 2000 Mar 1


  10. Block RI, O'Leary DS, Ehrhardt JC, Augustinack JC, Ghoneim MM, Arndt S, Hall JA: Effects of frequent marijuana use on brain tissue volume and composition. Neuroreport 2000 Feb 28


  11. Ghoneim MM: Awareness during anesthesia. Anesthesiology 2000 Feb 26


  12. Ghoneim MM, Block RI, Sarasin DS, Davis CS, Marchman JN: Tape-recorded hypnosis instructions as adjuvant in the care of patients scheduled for third molar surgery. Anesth Analg 2000 Jan 7


  13. Ghoneim MM, El-Zahaby HM, Block RI: Classical conditioning during nitrous oxide treatment: influence of varying the interstimulus interval. Pharmacol Biochem Behav 1999 Mar 18


  14. Ghoneim MM: Transient global amnesia: a cause for postanesthetic memory disorder. Anesth Analg 1998 Oct; 87(4):980-1


  15. Ghoneim MM, Block RI, Dhanaraj VJ: Interaction of a subanaesthetic concentration of isoflurane with midazolam: effects on responsiveness, learning and memory. Br J Anaesth 1998 Aug 6


  16. Ghoneim MM, Hinrichs JV: Drugs, memory, and sedation: specificity of effects [editorial; comment] Anesthesiology 1997 Oct; 87(4):734-6


  17. Ghoneim MM, Block RI: Learning and memory during general anesthesia: an update. Anesthesiology 1997 Aug 1


  18. Sarasin DS, Ghoneim MM, Block RI: Effects of sedation with midazolam or propofol on cognition and psychomotor functions. J Oral Maxillofac Surg 1996 Oct; 54(10):1187-93


  19. El-Zahaby HM, Ghoneim MM, Block RI: The interaction between nitrous oxide and isoflurane on suppression of learning: a study using classical conditioning in rabbits. Acta Anaesthesiol Scand 1996 Aug 1


  20. Ghoneim MM, Chen P, el-Zahaby HM, Block RI: Ketamine: acquisition and retention of classically conditioned responses during treatment with large doses. Pharmacol Biochem Behav 1994 Dec 1


  21. Block RI, Ghoneim MM: Insensitivity of implicit memory to anesthesia methods. Anesthesiology 1994 Aug; 81(2):516-7


  22. el-Zahaby HM, Ghoneim MM, Johnson GM, Gormezano I: Effects of subanesthetic concentrations of isoflurane and their interactions with epinephrine on acquisition and retention of the rabbit nictitating membrane response. Anesthesiology 1994 Jul 1


  23. Moon Y, Ghoneim MM, Gormezano I: Nitrous oxide: sensory, motor, associative, and behavioral tolerance effects in classical conditioning of the rabbit nictitating membrane response. Pharmacol Biochem Behav 1994 Mar; 47(3):523-9


  24. Ghoneim MM, Block RI, Ping ST, el-Zahaby HM, Hinrichs JV: The interactions of midazolam and flumazenil on human memory and cognition. Anesthesiology 1993 Dec 1


  25. Ghoneim MM, Block RI: Depth of anesthesia. Learning during anesthesia. Int Anesthesiol Clin 1993 Jan 1


  26. Block RI, Ghoneim MM: Effects of chronic marijuana use on human cognition. Psychopharmacology (Berl) 1993 Jan 1


  27. Ghoneim MM, Block RI, Fowles DC: No evidence of classical conditioning of electrodermal responses during anesthesia. Anesthesiology 1992 May 1


  28. Ghoneim MM, Block RI: Learning and consciousness during general anesthesia. Anesthesiology 1992 Feb 1


  29. Chen P, Ghoneim MM, Gormezano I: Sodium pentobarbital: sensory and associative effects in classical conditioning of the rabbit nictitating membrane response. Psychopharmacology (Berl) 1992 Jan 1


  30. Block RI, Ghoneim MM, Sum Ping ST, Ali MA: Efficacy of therapeutic suggestions for improved postoperative recovery presented during general anesthesia. Anesthesiology 1991 Nov 1


  31. Block RI, Ghoneim MM, Sum Ping ST, Ali MA: Human learning during general anaesthesia and surgery. Br J Anaesth 1991 Feb 1


  32. Block RI, Ghoneim MM, Kumar V, Pathak D: Psychedelic effects of a subanesthetic concentration of nitrous oxide. Anesth Prog 1990 Nov 1


  33. Ghoneim MM, Ali MA, Block RI: Appraisal of the quality of assessment of memory in anesthesia and psychopharmacology literature. Anesthesiology 1990 Nov 1


  34. Ghoneim MM, Block RI: The word "awareness": its ambiguous and confusing use in anesthesia literature on memory. Anesthesiology 1990 Jul; 73(1):193


  35. Ghoneim MM, Mewaldt SP: Benzodiazepines and human memory: a review. Anesthesiology 1990 May 1


  36. Block RI, Farnham S, Braverman K, Noyes R, Ghoneim MM: Long-term marijuana use and subsequent effects on learning and cognitive functions related to school achievement: preliminary study. NIDA Res Monogr 1990 Jan 1


  37. Korttila K, Ghoneim MM, Chiang CK, Nuotto E, Fischer LJ: Metabolites of methohexitone do not contribute to its prolonged action on the central nervous system. Acta Anaesthesiol Scand 1990 Jan; 34(1):55-8


  38. Block RI, Farnham S, Braverman K, Hinrichs JV, Ghoneim MM: Norms for free associations and five types of constrained associations. Psychol Rep 1989 Jun; 64(3 Pt 2):1065-6


  39. Ghoneim MM, Dembo JB, Block RI: Time course of antagonism of sedative and amnesic effects of diazepam by flumazenil. Anesthesiology 1989 Jun 1


  40. O'Hara MW, Ghoneim MM, Hinrichs JV, Mehta MP, Wright EJ: Psychological consequences of surgery. Psychosom Med 1989 May-Jun; 51(3):356-70


  41. Ghoneim MM, Hinrichs JV, O'Hara MW, Mehta MP, Pathak D, Kumar V, Clark CR: Comparison of psychologic and cognitive functions after general or regional anesthesia. Anesthesiology 1988 Oct 1


  42. Mewaldt SP, Ghoneim MM, Choi WW, Korttila K, Peterson RC: Nitrous oxide and human state-dependent memory. Pharmacol Biochem Behav 1988 May; 30(1):83-7


  43. Block RI, Ghoneim MM, Pathak D, Kumar V, Hinrichs JV: Effects of a subanesthetic concentration of nitrous oxide on overt and covert assessments of memory and associative processes. Psychopharmacology (Berl) 1988 Jan 1


  44. Fang JC, Hinrichs JV, Ghoneim MM: Diazepam and memory: evidence for spared memory function. Pharmacol Biochem Behav 1987 Nov; 28(3):347-52


  45. Block RI, Ghoneim MM, Fowles DC, Kumar V, Pathak D: Effects of a subanesthetic concentration of nitrous oxide on establishment, elicitation, and semantic and phonemic generalization of classically conditioned skin conductance responses. Pharmacol Biochem Behav 1987 Sep 1


  46. Ghoneim MM, Hinrichs JV, Mewaldt SP: Comparison of two benzodiazepines with differing accumulation: behavioral changes during and after 3 weeks of dosing. Clin Pharmacol Ther 1986 May; 39(5):491-500


  47. Ghoneim MM, Hinrichs JV, Chiang CK, Loke WH: Pharmacokinetic and pharmacodynamic interactions between caffeine and diazepam. J Clin Psychopharmacol 1986 Apr; 6(2):75-80


  48. Ghoneim MM, Chiang CK, Schoenwald RD, Lilburn JK, Dhanaraj J: The pharmacokinetics of methohexital in young and elderly subjects. Acta Anaesthesiol Scand 1985 Jul; 29(5):480-2


  49. Mehta MP, Dillman JB, Sherman BM, Ghoneim MM, Lemke JH: Etomidate anesthesia inhibits the cortisol response to surgical stress. Acta Anaesthesiol Scand 1985 Jul; 29(5):486-9


  50. Ghoneim MM, Hinrichs JV, Mewaldt SP, Petersen RC: Ketamine: behavioral effects of subanesthetic doses. J Clin Psychopharmacol 1985 Apr; 5(2):70-7


  51. Ghoneim MM, Mewaldt SP, Hinrichs JV: Behavioral effects of oral versus intravenous administration of diazepam. Pharmacol Biochem Behav 1984 Aug; 21(2):231-6


  52. Ghoneim MM, Dhanaraj J, Choi WW: Comparison of four opioid analgesics as supplements to nitrous oxide anesthesia. Anesth Analg 1984 Apr; 63(4):405-12


  53. Noyes R Jr, Anderson DJ, Clancy J, Crowe RR, Slymen DJ, Ghoneim MM, Hinrichs JV: Diazepam and propranolol in panic disorder and agoraphobia. Arch Gen Psychiatry 1984 Mar; 41(3):287-92


  54. Scamman FL, Ghoneim MM, Korttila K: Ventilatory and mental effects of alfentanil and fentanyl. Acta Anaesthesiol Scand 1984 Feb; 28(1):63-7


  55. Scamman FL, Ghoneim MM: How often may a Read rebreathing test be repeated? Clin Physiol 1983 Dec; 3(6):487-90


  56. Mewaldt SP, Hinrichs JV, Ghoneim MM: Diazepam and memory: support for a duplex model of memory. Mem Cognit 1983 Nov; 11(6):557-64


  57. Hinrichs JV, Mewaldt SP, Ghoneim MM, Berie JL: Diazepam and learning: assessment of acquisition deficits. Pharmacol Biochem Behav 1982 Jul; 17(1):165-70


  58. Korttila K, Ghoneim MM, Jacobs L, Lakes RS: Evaluation of instrumented force platform as a test to measure residual effects of anesthetics. Anesthesiology 1981 Dec; 55(6):625-30


  59. Ghoneim MM, Korttila K, Chiang CK, Jacobs L, Schoenwald RD, Mewaldt SP, Kayaba KO: Diazepam effects and kinetics in Caucasians and Orientals. Clin Pharmacol Ther 1981 Jun; 29(6):749-56


  60. Ghoneim MM: Mechanism of snoring [letter] JAMA 1981 May 1; 245(17):1729


  61. Korttila K, Ghoneim MM, Jacobs L, Mewaldt SP, Petersen RC: Time course of mental and psychomotor effects of 30 per cent nitrous oxide during inhalation and recovery. Anesthesiology 1981 Mar; 54(3):220-6


  62. Spector R, Choudhury AK, Chiang CK, Goldberg MJ, Ghoneim MM: Diphenhydramine in Orientals and Caucasians. Clin Pharmacol Ther 1980 Aug; 28(2):229-34


  63. Ghoneim MM: Antagonism of diazepam by physostigmine [letter] Anesthesiology 1980 Apr; 52(4):372-3


  64. Ghoneim MM: Thiopental: a current review of its pharmacology. Middle East J Anaesthesiol 1979 Oct; 5(5):351-5


  65. Ghoneim MM, Van Hamme MJ: Hydrolysis of etomidate. Anesthesiology 1979 Mar; 50(3):227-9


  66. Mewaldt SP, Ghoneim MM: The effects and interactions of scopolamine, physostigmine and methamphetamine on human memory. Pharmacol Biochem Behav 1979 Feb; 10(2):205-10


  67. Ghoneim MM, Van Hamme MJ: Pharmacokinetics of thiopentone: effects of enflurane and nitrous oxide anaesthesia and surgery. Br J Anaesth 1978 Dec; 50(12):1237-42


  68. Van Hamme MJ, Ghoneim MM, Ambre JJ: Pharmacokinetics of etomidate, a new intravenous anesthetic. Anesthesiology 1978 Oct; 49(4):274-7


  69. Van Hamme MJ, Ghoneim MM: A sensitive gas chromatograph assay for thiopentone in plasma. Br J Anaesth 1978 Feb; 50(2):143-5


  70. Van Hamme MJ, Ambre JJ, Ghoneim MM: Mass fragmentographic determination of plasma etomidate concentrations. J Pharm Sci 1977 Sep; 66(9):1344-6


  71. Ghoneim MM, Korttila K: Pharmacokinetics of intravenous anaesthetics: implications for clinical use. Clin Pharmacokinet 1977 Sep-Oct; 2(5):344-72


  72. Ghoneim MM, Yamada T: Etomidate: a clinical and electroencephalographic comparison with thiopental. Anesth Analg 1977 Jul-Aug; 56(4):479-85


  73. Ghoneim MM, Mewaldt SP: Studies on human memory: the interactions of diazepam, scopolamine, and physostigmine. Psychopharmacology (Berl) 1977 Mar 23; 52(1):1-6


  74. Ghoneim MM, Pandya HB, Kelley SE, Fischer LJ, Corry RJ: Binding of thiopental to plasma proteins: effects on distribution in the brain and heart. Anesthesiology 1976 Dec; 45(6):635-9


  75. Ghoneim MM, Mewaldt SP: Effects of diazepam and scopolamine on storage, retrieval and organizational processes in memory. Psychopharmacologia 1975 Nov 21; 44(3):257-62


  76. Ghoneim MM, Mewaldt SP, Thatcher JW: The effect of diazepam and fentanyl on mental, psychomotor and electroencephalographic functions and their rate of recovery. Psychopharmacologia 1975 Oct 14; 44(1):61-6


  77. Tucker GT, Mather LE, Ghoneim MM, Pandya H: Letter: Plasma protein binding of bupivacaine and its interaction with other drugs in man. Br J Anaesth 1975 Sep; 47(9):1029-30


  78. Ghoneim MM, Delle M, Wilson WR, Ambre JJ: Alteration of warfarin kinetics in man associated with exposure to an operating-room environment. Anesthesiology 1975 Sep; 43(3):333-6


  79. Ghoneim MM, Pandya H: Binding of tubocurarine to specific serum protein fractions. Br J Anaesth 1975 Aug; 47(8):853-6


  80. Ghoneim MM, Pandya H: Plasma protein binding of thiopental in patients with impaired renal or hepatic function. Anesthesiology 1975 May; 42(5):545-9


  81. Ghoneim MM, Mewaldt SP, Ambre J: Plasma levels of diazepam and mood ratings. Anesth Analg 1975 Mar-Apr; 54(2):173-7


  82. Ghoneim MM, Pandya H: Plasma protein binding of bupivacaine and its interaction with other drugs in man. Br J Anaesth 1974 Jun; 46(6):435-8


  83. Ghoneim MM, Kramer E, Bannow R, Pandya H, Routh JI: Binding of d-tubocurarine to plasma proteins in normal man and in patients with hepatic or renal disease. Anesthesiology 1973 Oct; 39(4):410-5


  84. Ghoneim MM: Flurazepam (Dalmane)--a new hypnotic. J Iowa Med Soc 1973 Sep; 63(9):444-6


  85. Ghoneim MM: Neostigmine antagonism of neuromuscular block. Anesthesiology 1973 May; 38(5):511-2


  86. Dretchen K, Ghoneim MM, Long JP: Interactions of serotonin with neuromuscular blocking agents. Eur J Pharmacol 1972 Apr; 18(1):121-7


  87. Ghoneim MM, Urgena RB, Dretchen K, Long JP: The interaction between d-tubocurarine and gallamine during halothane anaesthesia. Can Anaesth Soc J 1972 Jan; 19(1):66-74


  88. Ghoneim MM: Drug interaction in anaesthesia. A review. Can Anaesth Soc J 1971 Jul; 18(4):353-75


  89. Ghoneim MM: Drug interactions in anesthesia. J Iowa Med Soc 1971 May; 61(5):294 passim


  90. Dretchen K, Ghoneim MM, Long JP: The interaction of diazepam with myoneural blocking agents. Anesthesiology 1971 May; 34(5):463-8


  91. Ghoneim MM: [Magnesium-ion physiology. Anesthesiology 1970 Sep; 33(3):373


  92. Ghoneim MM, Long JP: The interaction between magnesium and other neuromuscular blocking agents. Anesthesiology 1970 Jan; 32(1):23-7
Intranet | Site Map | Terms Of Use | Privacy Statement

Copyright 1998-2009 by the University of Iowa Department of Anesthesia