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Dr. Todd

The Department of Anesthesia at the University of Iowa is a leader in clinical and basic science research. Clinical investigations occur in all subspecialties including critical care and cardiothoracic, neurosurgical, and regional anesthesia. Basic science research topics are pain, analgesic pharmacology and learning and memory. There is an emphasis on training physicians and scientists on the fundamentals of basic and clinical research. The Department of Anesthesia is keenly interested in providing residents and fellows with the background for developing a career in research.

Surgical Intensive Care Unit Research

Operations Research

Pain Research



 
Grants Recently Awarded and Submitted

Grants Recently Awarded

12/2009 NIH, $1,687,500, Donna Hammond, PI, “Opioid Mechanisms of Analgesia.”
09/2009 NIH, $1,380,000, Timothy Brennan, PI,“Nociception from Deep Muscle Incision.”
09/2009 NIH, Timothy Brennan, Co-I, $91,575, “Complement System Modulation of Nociception and Inflammation after Incision.”
09/2009 American Burn Association Grant, $25,000, Anthony Han, PI, “Clinical Pharmacology of Ketamine for Procedural Sedation in the Pediatric Burn Patients.”
07/2009 NIH, $1,095,000, Toshihiro Kitamoto, PI, “Studies of Genes Involved in the Lithium Responsive Neurological Process.”
07/2009 NIH T32, Donna Hammond, PI, “Interdisciplinary Training Program in Pain Research,” 4 trainee positions supported.

Submitted Grants

11/2009 International Anesthesia Research Society (IARS), Anthony Han, PI, “Closed Loop Control of Intracranial Pressure: Development of a Novel Continuous Infusion Regimen for 20% Mannitol vs. 3% Hypertonic Saline.”
11/2009 International Anesthesia Research Society (IARS), Joss Thomas, PI, “Iowa Outcomes with Anesthesia Adolescent Study (IOWAA Study).”
10/2009 NIH K08, Christina Spofford, PI, “Acute Post Laminectomy Pain and Aging: Molecular Mechanisms.”
10/2009 NIH R01, Bradley Hindman, PI, “Biomechanical Analysis and Modeling of Cervical Spine Motion during Intubation.”
09/2009  NIH R01, Robert Block, PI,  “General Anesthesia during Human Infancy and Brain Development.”
08/2009 NIH/FDA, Children’s Hospital of Boston. Joss Thomas, Co-I, “A Multi-Site RCT Comparing Regional and General Anesthesia for Effects on Neurodevelopmental Outcome and Apnea in Infants: The GAS Study.”
07/2009 March of Dimes, Joss Thomas, PI, “Iowa Outcomes with Anesthesia (IOWA) study.”
06/2009 Anesthesia Patient Safety Foundation, Mazen Maktabi, PI, “An Epidemiological Study of Preoperative Cognitive Impairment as a Risk Factor for Postoperative Delirium Older Adults Undergoing Noncardiac Surgery.”
06/2009 NIH ARRA Grant, James Bates, Co-I, Project 3 of PPG: “Cellular S-nitrosothiol Signaling in Respiratory Biology.”

 
Investigator Spotlight: Max T. Baker, Ph.D.

Dr. BakerI received my doctorate in pharmacology at the University of Georgia College of Pharmacy studying the effects of dietary fats on carcinogen metabolic activation. After a postdoctoral fellowship at the Mayo Clinic, where I studied the metabolism of anesthetics and halogenated compounds by the cytochrome P450 enzyme system, I came to The University of Iowa in 1984. At the time, there was interest in the metabolism and toxicity of small fluorinated compounds as they were employed not only as anesthetics but as the new non-chlorinated refrigerant substitutes. Read more...
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